Sperm Count for IUI Treatment - Sperm count and pregnancy with IUI(Intrauterine insemination)Treatment

IUI is a fertility treatment that is commonly used to treat infertility caused by ovulation issues, endometriosis, or mild male factor infertility. IUI success is mainly dependent on the amount and quality of sperm, in addition to female fertility and ovulation. IUI success rates are often lower in men with low sperm count or sperm motility (the ability of sperm to migrate towards the egg).

What is IUI?

On the day of the IUI process, a sperm sample is collected from the male. Before being put into the female’s uterine cavity, the sperm sample is first “washed” or processed in the laboratory. The sperm must be able to swim to the fallopian tubes, where they will meet the egg for fertilization, after being injected into the uterine cavity.

IUI Success Requires Sperm Count

Because IUI relies on the ability of the sperm to swim and find the egg, a high sperm count and motility are required for a successful procedure. For an IUI to be successful, the number of motile sperm after processing the sperm sample should be around 5 million or higher. A sample with 1 to 5 million motile cells has a much-reduced success rate, while processed sperm samples with less than 1 million motile sperm cells are very unlikely to result in successful fertilization. In vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) are recommended instead of IUI for men with low sperm counts.

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IUI success rates for male factor fertility problems

Depending on the treatment strategy, the success rate of IUI for male infertility varies. Medicated IUI cycles had a greater success rate than unmedicated IUI cycles.

  • Pregnancy rates for unmedicated IUI cycles range from 6 to 10% every cycle.
  • Pregnancy rates for IUI cycles with Clomid range from 8 to 12 percent per cycle.
  • Letrozole (Femara) IUI cycles had a pregnancy rate of 10-15% per cycle.
  • Pregnancy rates for IUI cycles with gonadotropins range from 20 to 25 percent per cycle.
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